Synthesis of new heterocyclic dehydroabietylamine derivatives and their biological activity

Kseniya S. Kovaleva, Olga I. Yarovaya, Andrey V. Shernyukov, Vladimir V. Zarubaev, Anna A. Shtro, Yana R. Orshanskaya, Nariman F. Salakhutdinov

Research output: Contribution to journalArticlepeer-review

8 Citations (Scopus)

Abstract

New derivatives of dehydroabietylamine were obtained by transformation of primary amino group to pyrrolidine, piperidine, azepane, morpholine, isoindoline, and pyrrole heterocycles. The obtained compounds were tested for antiviral activity against influenza A/California/07/09 (H1N1)pdm09 strain, as well as the activity against some types of bacteria and fungi.

Original languageEnglish
Pages (from-to)364-370
Number of pages7
JournalChemistry of Heterocyclic Compounds
Volume53
Issue number3
DOIs
Publication statusPublished - 1 Mar 2017

Keywords

  • Antibacterial activity
  • Antiviral activity
  • Dehydroabietylamine
  • Natural compounds
  • antibacterial activity
  • OXIDATION
  • natural compounds
  • PYRROLES
  • antiviral activity
  • (+)-DEHYDROABIETYLAMINE
  • PHTHALIMIDE
  • dehydroabietylamine
  • EFFICIENT

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