Study of product composition of the reaction between 1,1,2,2-tetrabromoethane and imidazole or 1,2,4-triazole in a superbasic medium

Maxim Klyuchenko, Pulat Kadirov, Anastasiya Kuznetsova, Andrei Potapov

Research output: Chapter in Book/Report/Conference proceedingConference contributionResearchpeer-review

Abstract

Influence of reagent ratio on the composition of products of the reaction between 1,1,2,2-tetrabromoethane and imidazole or 1,2,4-triazole in a superbasic medium (potassium hydroxide - dimethyl sulfoxide) was investigated using GC/MS technique. It was found that nucleophilic substitution reaction is always accompanied by elimination reactions (dehydrobromination and debromination). In addition to 1,1,2,2-tetra(azol-1-yl)ethane, 1,1,2-tri(azol-1-yl)ethenes and 1,2-di(azol-1-yl)ethenes, as well as 1,2-di(azol-1-yl)-1-bromoethenes were detected. Reaction pathway that explains the formation of all major products was proposed.

Original languageEnglish
Title of host publication19TH INTERNATIONAL ELECTRONIC CONFERENCE ON SYNTHETIC ORGANIC CHEMISTRY
EditorsJA Seijas, MPV Tato, SK Lin
PublisherMDPI AG
Number of pages6
DOIs
Publication statusPublished - 2015
Externally publishedYes
Event19th International Electronic Conference on Synthetic Organic Chemistry -
Duration: 1 Nov 201530 Nov 2015

Conference

Conference19th International Electronic Conference on Synthetic Organic Chemistry
Period01.11.201530.11.2015

Keywords

  • imidazole
  • triazole
  • terabromoethane
  • superbasic medium
  • nucleophilic substitution
  • elimination
  • COMPLEXES
  • LIGANDS
  • DESIGN

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