Rescue of the karyotype with ring chromosome 8 in human induced pluripotent stem cells

T. V. Nikitina; M. M. Gridina; Y. M. Minina; A. A. Kashevarova; Y. S. Yakovleva; D. A. Fedotov; M. E. Lopatkina; S. A. Vasilyev; O. L. Serov; I. N. Lebedev

doi:10.1038/s41431-020-00739-z

Rescue of the karyotype with ring chromosome 8 in human induced pluripotent stem cells

T. V. Nikitina, M. M. Gridina, Y. M. Minina, A. A. Kashevarova, Y. S. Yakovleva, D. A. Fedotov, M. E. Lopatkina, S. A. Vasilyev, O. L. Serov, I. N. Lebedev

Cytology and Genetics Section

Research output: Contribution to journal › Meeting Abstract › peer-review

Abstract

Introduction: Ring chromosomes are usually found as a part of mosaic karyotype and dynamic mosaicism is a frequent event in the patient’s cells. Induced pluripotent stem cells (iPSCs) proved to be a valuable tool for the modelling of the dynamics of ring chromosome mosaicism through multiple cell divisions.

Original language	English
Article number	P14.35.A
Pages (from-to)	587-587
Number of pages	1
Journal	European journal of human genetics
Volume	28
Issue number	Suppl 1
DOIs	https://doi.org/10.1038/s41431-020-00739-z
Publication status	Published - Dec 2020
Event	53rd Conference of the European-Society-of-Human-Genetics (ESHG) - Virtual Conference Duration: 6 Jun 2020 → 9 Jun 2020 Conference number: 53

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Nikitina, T. V., Gridina, M. M., Minina, Y. M., Kashevarova, A. A., Yakovleva, Y. S., Fedotov, D. A., Lopatkina, M. E., Vasilyev, S. A., Serov, O. L., & Lebedev, I. N. (2020). Rescue of the karyotype with ring chromosome 8 in human induced pluripotent stem cells. European journal of human genetics, 28(Suppl 1), 587-587. [P14.35.A]. https://doi.org/10.1038/s41431-020-00739-z

@article{a38a91f74825466ca281f9a6f117a07b,

title = "Rescue of the karyotype with ring chromosome 8 in human induced pluripotent stem cells",

abstract = "Introduction: Ring chromosomes are usually found as a part of mosaic karyotype and dynamic mosaicism is a frequent event in the patient{\textquoteright}s cells. Induced pluripotent stem cells (iPSCs) proved to be a valuable tool for the modelling of the dynamics of ring chromosome mosaicism through multiple cell divisions.",

author = "Nikitina, {T. V.} and Gridina, {M. M.} and Minina, {Y. M.} and Kashevarova, {A. A.} and Yakovleva, {Y. S.} and Fedotov, {D. A.} and Lopatkina, {M. E.} and Vasilyev, {S. A.} and Serov, {O. L.} and Lebedev, {I. N.}",

note = "This study was supported by Russian Science Foundation, grant 16-15-10231.; 53rd Conference of the European-Society-of-Human-Genetics (ESHG), ESHG ; Conference date: 06-06-2020 Through 09-06-2020",

year = "2020",

month = dec,

doi = "10.1038/s41431-020-00739-z",

language = "English",

volume = "28",

pages = "587--587",

journal = "European journal of human genetics",

issn = "1018-4813",

publisher = "Nature Publishing Group",

number = "Suppl 1",

}

Rescue of the karyotype with ring chromosome 8 in human induced pluripotent stem cells. / Nikitina, T. V.; Gridina, M. M.; Minina, Y. M.; Kashevarova, A. A.; Yakovleva, Y. S.; Fedotov, D. A.; Lopatkina, M. E.; Vasilyev, S. A.; Serov, O. L.; Lebedev, I. N.

In: European journal of human genetics, Vol. 28, No. Suppl 1, P14.35.A, 12.2020, p. 587-587.

Research output: Contribution to journal › Meeting Abstract › peer-review

TY - JOUR

T1 - Rescue of the karyotype with ring chromosome 8 in human induced pluripotent stem cells

AU - Nikitina, T. V.

AU - Gridina, M. M.

AU - Minina, Y. M.

AU - Kashevarova, A. A.

AU - Yakovleva, Y. S.

AU - Fedotov, D. A.

AU - Lopatkina, M. E.

AU - Vasilyev, S. A.

AU - Serov, O. L.

AU - Lebedev, I. N.

N1 - Conference code: 53

PY - 2020/12

Y1 - 2020/12

N2 - Introduction: Ring chromosomes are usually found as a part of mosaic karyotype and dynamic mosaicism is a frequent event in the patient’s cells. Induced pluripotent stem cells (iPSCs) proved to be a valuable tool for the modelling of the dynamics of ring chromosome mosaicism through multiple cell divisions.

AB - Introduction: Ring chromosomes are usually found as a part of mosaic karyotype and dynamic mosaicism is a frequent event in the patient’s cells. Induced pluripotent stem cells (iPSCs) proved to be a valuable tool for the modelling of the dynamics of ring chromosome mosaicism through multiple cell divisions.

U2 - 10.1038/s41431-020-00739-z

DO - 10.1038/s41431-020-00739-z

M3 - Meeting Abstract

C2 - 33262485

VL - 28

SP - 587

EP - 587

JO - European journal of human genetics

JF - European journal of human genetics

SN - 1018-4813

IS - Suppl 1

M1 - P14.35.A

T2 - 53rd Conference of the European-Society-of-Human-Genetics (ESHG)

Y2 - 6 June 2020 through 9 June 2020

ER -

Rescue of the karyotype with ring chromosome 8 in human induced pluripotent stem cells

Abstract

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