Abstract
15N spin-lattice relaxation dynamics in metronidazole- 15N 3 and metronidazole- 15N 2 isotopologues are studied for rational design of 15N-enriched biomolecules for signal amplification by reversible exchange in microtesla fields. 15N relaxation dynamics mapping reveals the deleterious effects of interactions with the polarization transfer catalyst and a quadrupolar 14N nucleus within the spin-relayed 15N- 15N network.
Original language | English |
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Pages (from-to) | 9098-9101 |
Number of pages | 4 |
Journal | Chemical Communications |
Volume | 56 |
Issue number | 64 |
DOIs | |
Publication status | Published - 18 Aug 2020 |
Keywords
- REVERSIBLE EXCHANGE
- SIGNAL AMPLIFICATION
- CATALYSTS
- MRI