Abstract
Current view on a relationship between particle pollution, morbidity and mortality of lung carcinoma were discussed in the article. Published epidemiological, clinical and laboratory studies suggest particle pollution, especially metal containing particulate matter (PM), to be a risk factor for lung carcinoma occurrence. PM-associated injury of epithelial cell genome and epigenetic lesions are an important part of pathogenesis of lung carcinoma. Systemic research findings and formalized reports could improve our knowledge on lung cancer pathogenesis and could be used in clinical practice for risk assessment, early detection and prognosis of lung cancer and improvement in treatment efficacy.
Translated title of the contribution | Загрязнение атмосферного воздуха взвешенными веществами как фактор риска рака легких |
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Original language | English |
Pages (from-to) | 477-485 |
Number of pages | 9 |
Journal | Pulmonologiya |
Volume | 29 |
Issue number | 4 |
DOIs | |
Publication status | Published - 1 Jan 2019 |
Keywords
- Air pollution
- Lung carcinoma
- Particulate matter
- Pathogenesis
State classification of scientific and technological information
- 76 MEDICINE AND HEALTH CARE