Origin and evolution of the neo-sex chromosomes in pamphagidae grasshoppers through chromosome fusion and following heteromorphization

Ilyas Yerkinovich, Alexander Gennadievich Bugrov, Olesya Georgievna Buleu, Anton Gennadievich Bogomolov, Nikolay Borisovich Rubtsov

Research output: Contribution to journalArticlepeer-review

5 Citations (Scopus)

Abstract

In most phylogenetic lineages, the evolution of sex chromosomes is accompanied by their heteromorphization and degradation of one of them. The neo-sex chromosomes are useful model for studying early stages of these processes. Recently two lineages of the neo-sex chromosomes on different stages of heteromorphization was discovered in Pamphagidae family. The neo-sex chromosome heteromorphization was analyzed by generation of DNA probes derived from the neo- Xs and neo-Ys followed with chromosome painting in nineteen species of Pamphagidae family. The homologous regions of the neo-sex chromosomes were determined in closely related species with the painting procedure and image analysis with application of the Visualization of the Specific Signal in Silico software package. Results of these analyses and distribution of C-positive regions in the neo-sex chromosomes revealed details of the heteromorphization of the neo-sex chromosomes in species from both phylogenetic lineages of Pamphagidae grasshoppers. The hypothetical mechanism of the neo-Y degradation was suggested. It includes expansion of different repeats from the proximal neo-Y chromosome region by inversions, spreading them towards distal region. Amplification of these repeats leads to formation of C-positive regions and elimination of the Cnegative regions located between them.

Original languageEnglish
Article number323
Number of pages20
JournalGenes
Volume8
Issue number11
DOIs
Publication statusPublished - 13 Nov 2017

Keywords

  • Chromosome
  • Chromosome microdissection
  • Chromosome painting
  • DNA libraries
  • Evolution
  • Fluorescent in situ hybridization
  • Grasshoppers
  • Neo-sex
  • Neo-X
  • Neo-Y
  • Pamphagidae
  • 25-COLOR FISH
  • SATELLITE DNA
  • neo-sex
  • chromosome microdissection
  • ORTHOPTERA
  • grasshoppers
  • Y-CHROMOSOME
  • neo-Y
  • neo-X
  • B-CHROMOSOMES
  • chromosome
  • HYBRIDIZATION
  • evolution
  • DEGENERATION
  • chromosome painting
  • COMPARATIVE FISH ANALYSIS
  • DYNAMICS
  • MICRODISSECTION

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