Molecular biological problems of drug design and mechanism of drug action: Organic hydrogen sulfide donor compounds with cardioprotective properties (review)

N. I. Tkacheva, S. V. Morozov, B. B. Lomivorotov, I. A. Grigor’ev

Research output: Contribution to journalReview articlepeer-review

2 Citations (Scopus)

Abstract

This review summarizes published data on organic hydrogen sulfide donor compounds, including hybrid compounds, and their roles in cardioprotection.

Original languageEnglish
Pages (from-to)165-174
Number of pages10
JournalPharmaceutical Chemistry Journal
Volume51
Issue number3
DOIs
Publication statusPublished - Jun 2017

Keywords

  • Cardioprotection
  • Cardiovascular system
  • Hybrid compounds
  • Hydrogen sulfide
  • Organic HS donors
  • cardiovascular system
  • EFFECTS IN-VITRO
  • PLATELET-AGGREGATION
  • MUSCLE-CELL PROLIFERATION
  • MYOCARDIAL-ISCHEMIA
  • MEDIATES CARDIOPROTECTION
  • hybrid compounds
  • ISCHEMIA-REPERFUSION INJURY
  • H2S DONORS
  • S-PROPARGYL-CYSTEINE
  • hydrogen sulfide
  • organic H2S donors
  • cardioprotection
  • NITRIC-OXIDE
  • PHARMACOLOGICAL EVALUATION

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