On the Impact of Flow-Diverters on the Hemodynamics of Human Cerebral Aneurysms

D. V. Parshin; Yu O. Kuyanova; D. S. Kislitsin; U. Windberger; A. P. Chupakhin

doi:10.1134/S0021894418060019

On the Impact of Flow-Diverters on the Hemodynamics of Human Cerebral Aneurysms

D. V. Parshin, Yu O. Kuyanova, D. S. Kislitsin, U. Windberger, A. P. Chupakhin

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2 Citations (Scopus)

Abstract

The impact of flow-diverters used for cerebral aneurysm treatment on human brain hemodynamics was evaluated qualitatively and quantitatively. Numerical simulation of flow-diverter placement in cerebral vessels with aneurysms was carried out for the case history of a real patient using the commercial ANSYS 17.2 package with different (Newtonian and non-Newtonian) hydrodynamic models for blood rheology in different parts of the vessel and aneurysm, which is due to experimental data. It is shown that after flow-diverter placement, the blood flow through the artery segment containing the aneurysm neck decreases, resulting in a redistribution of the cerebral blood flow, which becomes close to the blood flow in healthy subjects. Changes in wall shear stresses in the flow-diverter region are indicative of possible aneurysm recanalization.

Original language	English
Pages (from-to)	963-970
Number of pages	8
Journal	Journal of Applied Mechanics and Technical Physics
Volume	59
Issue number	6
DOIs	https://doi.org/10.1134/S0021894418060019
Publication status	Published - 1 Nov 2018

Keywords

brain hemodynamics
cerebral aneurysm
flow-diverter
non-Newtonian blood rheology
reconstruction of DICOM images

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10.1134/S0021894418060019

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title = "On the Impact of Flow-Diverters on the Hemodynamics of Human Cerebral Aneurysms",

abstract = "The impact of flow-diverters used for cerebral aneurysm treatment on human brain hemodynamics was evaluated qualitatively and quantitatively. Numerical simulation of flow-diverter placement in cerebral vessels with aneurysms was carried out for the case history of a real patient using the commercial ANSYS 17.2 package with different (Newtonian and non-Newtonian) hydrodynamic models for blood rheology in different parts of the vessel and aneurysm, which is due to experimental data. It is shown that after flow-diverter placement, the blood flow through the artery segment containing the aneurysm neck decreases, resulting in a redistribution of the cerebral blood flow, which becomes close to the blood flow in healthy subjects. Changes in wall shear stresses in the flow-diverter region are indicative of possible aneurysm recanalization.",

keywords = "brain hemodynamics, cerebral aneurysm, flow-diverter, non-Newtonian blood rheology, reconstruction of DICOM images",

author = "Parshin, {D. V.} and Kuyanova, {Yu O.} and Kislitsin, {D. S.} and U. Windberger and Chupakhin, {A. P.}",

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AU - Parshin, D. V.

AU - Kuyanova, Yu O.

AU - Kislitsin, D. S.

AU - Windberger, U.

AU - Chupakhin, A. P.

PY - 2018/11/1

Y1 - 2018/11/1

N2 - The impact of flow-diverters used for cerebral aneurysm treatment on human brain hemodynamics was evaluated qualitatively and quantitatively. Numerical simulation of flow-diverter placement in cerebral vessels with aneurysms was carried out for the case history of a real patient using the commercial ANSYS 17.2 package with different (Newtonian and non-Newtonian) hydrodynamic models for blood rheology in different parts of the vessel and aneurysm, which is due to experimental data. It is shown that after flow-diverter placement, the blood flow through the artery segment containing the aneurysm neck decreases, resulting in a redistribution of the cerebral blood flow, which becomes close to the blood flow in healthy subjects. Changes in wall shear stresses in the flow-diverter region are indicative of possible aneurysm recanalization.

AB - The impact of flow-diverters used for cerebral aneurysm treatment on human brain hemodynamics was evaluated qualitatively and quantitatively. Numerical simulation of flow-diverter placement in cerebral vessels with aneurysms was carried out for the case history of a real patient using the commercial ANSYS 17.2 package with different (Newtonian and non-Newtonian) hydrodynamic models for blood rheology in different parts of the vessel and aneurysm, which is due to experimental data. It is shown that after flow-diverter placement, the blood flow through the artery segment containing the aneurysm neck decreases, resulting in a redistribution of the cerebral blood flow, which becomes close to the blood flow in healthy subjects. Changes in wall shear stresses in the flow-diverter region are indicative of possible aneurysm recanalization.

KW - brain hemodynamics

KW - cerebral aneurysm

KW - flow-diverter

KW - non-Newtonian blood rheology

KW - reconstruction of DICOM images

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On the Impact of Flow-Diverters on the Hemodynamics of Human Cerebral Aneurysms

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Keywords

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