On the Impact of Flow-Diverters on the Hemodynamics of Human Cerebral Aneurysms

D. V. Parshin, Yu O. Kuyanova, D. S. Kislitsin, U. Windberger, A. P. Chupakhin

Research output: Contribution to journalArticlepeer-review

2 Citations (Scopus)

Abstract

The impact of flow-diverters used for cerebral aneurysm treatment on human brain hemodynamics was evaluated qualitatively and quantitatively. Numerical simulation of flow-diverter placement in cerebral vessels with aneurysms was carried out for the case history of a real patient using the commercial ANSYS 17.2 package with different (Newtonian and non-Newtonian) hydrodynamic models for blood rheology in different parts of the vessel and aneurysm, which is due to experimental data. It is shown that after flow-diverter placement, the blood flow through the artery segment containing the aneurysm neck decreases, resulting in a redistribution of the cerebral blood flow, which becomes close to the blood flow in healthy subjects. Changes in wall shear stresses in the flow-diverter region are indicative of possible aneurysm recanalization.

Original languageEnglish
Pages (from-to)963-970
Number of pages8
JournalJournal of Applied Mechanics and Technical Physics
Volume59
Issue number6
DOIs
Publication statusPublished - 1 Nov 2018

Keywords

  • brain hemodynamics
  • cerebral aneurysm
  • flow-diverter
  • non-Newtonian blood rheology
  • reconstruction of DICOM images

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