Numerical Method for Predicting Hemodynamic Effects in Vascular Prostheses

V. G. Borisov, Yu N. Zakharov, Yu I. Shokin, E. A. Ovcharenko, K. Yu Klyshnikov, I. N. Sizova, A. V. Batranin, Yu A. Kudryavtseva, P. S. Onishchenko

Research output: Contribution to journalArticlepeer-review


A three-dimensional unsteady periodic flow of blood in xenogenic vascular bioprostheses is simulated by computational fluid dynamics methods. The geometry of the computational domain is based on microtomographic scanning of bioprostheses. To set a variable pressure gradient causing an unsteady flow in the prostheses, personal-specific data of the Doppler echography of the blood flow of a particular patient are used. A comparative analysis of the velocity fields in the flow areas corresponding to three real samples of bioprostheses with multiple stenoses is carried out. In the zones of stenosis and outside of them, the distribution of the near-wall shear stress, which affects the risk factors for thrombosis in the prostheses, is analyzed. An algorithm for predicting the hemodynamic effects arising in vascular bioprostheses is proposed; the algorithm is based on the numerical modeling of the blood flow in these prostheses.

Original languageEnglish
Pages (from-to)326-337
Number of pages12
JournalNumerical Analysis and Applications
Issue number4
Publication statusPublished - 1 Oct 2019
Externally publishedYes


  • bioprostheses
  • blood flow
  • computer modeling
  • wall shear stress

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