Lymph nodes morphology as predictor natural and premature aging

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Abstract

The research purpose is to estimate the structural organization of lymph nodes of different localization at natural (physiological) and premature aging respectively at OXYS and Wistar rats. We used a morphological method of a research. The age-induced changes of lymphoid tissue of Wistar and OXYS rats differ with type of the immune response and morphological variant of lymph nodes structure. The immune response on humoral type is formed in mesenteric and inguinal lymph nodes, and the immune response on cellular type is formed in a tracheobronchial lymph node. We noted reduction of structures of cortical substance, especially lymphoid follicles and a paracortex, and expansion of medullary substance in a lymph node of OXYS rats. Lymph nodes are subject big morphological changes at rats of OXYS, than at old rats of Wistar. Observed changes of structure of lymph nodes of OXYS rats are a morphological equivalent of premature aging and confirms early decrease of a drainage and immune function of lymph nodes
Original languageEnglish
Title of host publicationLymph nodes morphology as predictor natural and premature aging
Subtitle of host publicationBioinformatics of Genome Regulation and Structure Systems Biology (BGRS/SB-2020): The Twelfth International Multiconference (06-10 July 2020, Novosibirsk, Russia)
Place of PublicationNovosibirsk: ICG SB RAS
PublisherInstitute of Cytology and Genetics of Siberian Branch of the Russian Academy of Sciences
Pages642-643
Number of pages2
ISBN (Print)978-5-91291-051-7
DOIs
Publication statusPublished - Jul 2020
EventBioinformatics of Genome Regulation and Structure Systems Biology (BGRS/SB-2020): The Twelfth International Multiconference (06-10 July 2020, Novosibirsk, Russia) - ICG SB RAS, Новосибирск, Russian Federation
Duration: 6 Jul 202010 Jul 2020
Conference number: 12
https://bgrssb.icgbio.ru/2020/

Conference

ConferenceBioinformatics of Genome Regulation and Structure Systems Biology (BGRS/SB-2020): The Twelfth International Multiconference (06-10 July 2020, Novosibirsk, Russia)
Abbreviated titleBGRS/SB-2020
CountryRussian Federation
CityНовосибирск
Period06.07.202010.07.2020
Internet address

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