A simple approach for isolation of exosomes from blood plasma samples has been proposed. Using this approach it is possible to obtain highly purified preparations of microvesicles no larger than 100 nm. The presence of different subpopulations of exosomes isolated by this method has been recognized in the blood plasma of healthy donors and cancer patients. Universal markers CD9, CD24, and CD81 are applicable for routine typing of exosomes isolated from blood plasma samples.
|Number of pages||5|
|Journal||Biochemistry (Moscow) Supplement Series B: Biomedical Chemistry|
|Publication status||Published - 1 Jul 2017|
- breast cancer
- colorectal cancer
- flow cytometry
- transmission electron microscopy