Influenza Antiviral Activity of Br-Containing [2R,4R(S),4aR,7R,8aR]-4,7-Dimethyl-2-(Thiophen-2-YL)Octahydro-2H-Chromen-4-Ols Prepared from (–)-Isopulegol

E. V. Nazimova, A. A. Shtro, V. B. Anikin, O. S. Patrusheva, I. V. Il′ina, D. V. Korchagina, V. V. Zarubaev, K. P. Volcho, N. F. Salakhutdinov

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    15 Citations (Scopus)

    Abstract

    Influenza A (H1N1) antiviral activity of compounds with an octahydro-2H-chromene skeleton that were prepared by reacting the monoterpenoid (–)-isopulegol and thiophenecarboxaldehyde and its derivatives was studied for the first time. The 5-bromothiophene-2-carboxaldehyde derivative exhibited the greatest antiviral activity.

    Original languageEnglish
    Pages (from-to)260-264
    Number of pages5
    JournalChemistry of Natural Compounds
    Volume53
    Issue number2
    DOIs
    Publication statusPublished - 1 Mar 2017

    Keywords

    • antiviral activity
    • clay
    • heterocyclic compounds
    • influenza A
    • monoterpenes
    • thiophenecarboxaldehyde

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