In silico modeling gas molecules transfer through the biomembrane by kinks-solitons

P. V. Mokrushnikov, E. V. Lezhnev, V. Ya Rudyak

Research output: Chapter in Book/Report/Conference proceedingConference contributionResearchpeer-review

Abstract

It is shown that the mechanism of the gas molecules transfer through the lipid bilayer can be connected with the kink-solitons. They are appeared in the lipid bilayer as a result of structural changes in biomembranes. The analytical model describing the behavior of kink-solitons in the finite hydrocarbon chain is presented. The kink-solitons are formed during the folding of the erythrocyte as it moves along the microcapillaries. The equation of the kink-soliton motion is derived. This equation is numerically solved. It is shown that kink-solitons can appear in both saturated and unsaturated alkyl chains. In unsaturated chains, the soliton is "smeared out,"CH2-groups vibrate around C=C bonds with a significant amplitude, taking away part of the soliton's energy. The transport of gas molecules by kink-solitons in unsaturated chains is hindered in comparison with saturated hydrocarbon chains. When the mechanical stress field changes, a sharp change in membrane permeability occurs.

Original languageEnglish
Title of host publicationInternational Conference on the Methods of Aerophysical Research, ICMAR 2020
EditorsVasily M. Fomin, Alexander Shiplyuk
PublisherAmerican Institute of Physics Inc.
ISBN (Electronic)9780735440999
DOIs
Publication statusPublished - 24 May 2021
Event20th International Conference on the Methods of Aerophysical Research, ICMAR 2020 - Akademgorodok, Novosibirsk, Russian Federation
Duration: 1 Nov 20207 Nov 2020

Publication series

NameAIP Conference Proceedings
Volume2351
ISSN (Print)0094-243X
ISSN (Electronic)1551-7616

Conference

Conference20th International Conference on the Methods of Aerophysical Research, ICMAR 2020
CountryRussian Federation
CityAkademgorodok, Novosibirsk
Period01.11.202007.11.2020

OECD FOS+WOS

  • 1.03 PHYSICAL SCIENCES AND ASTRONOMY

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