Genetic Organization of Open Chromatin Domains Situated in Polytene Chromosome Interbands in Drosophila

T. Yu Zykova, O. O. Popova, V. A. Khoroshko, V. G. Levitsky, S. A. Lavrov, I. F. Zhimulev

Research output: Contribution to journalArticlepeer-review

2 Citations (Scopus)

Abstract

New data on the organization of genes entirely located in the open domains for chromatin transcription and occupying only one chromosome structure (interband) were obtained. The characteristic features of these genes are the small size (on average, 1–2 kb), depletion of the replicative complex proteins in the regulatory region, and the presence of specific motifs for binding transcription factors, as compared to the genes occupying two structures (interband and gray band). The biological function of these genes is associated primarily with the processes of gene expression and RNA metabolism.

Original languageEnglish
Pages (from-to)297-301
Number of pages5
JournalDoklady Biochemistry and Biophysics
Volume483
Issue number1
DOIs
Publication statusPublished - 1 Nov 2018

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