Generation of induced pluripotent stem cell lines ICGi021-A and ICGi022-A from peripheral blood mononuclear cells of two healthy individuals from Siberian population

A. A. Malakhova, E. V. Grigor'eva, S. V. Pavlova, T. B. Malankhanova, K. R. Valetdinova, Y. V. Vyatkin, E. A. Khabarova, J. A. Rzaev, S. M. Zakian, S. P. Medvedev

Research output: Contribution to journalArticlepeer-review

Abstract

ICGi021-A and ICGi022-A iPSC lines were obtained by reprogramming PBMCs of two healthy women of the Siberian population using episomal non-integrating vectors expressing Yamanaka factors. iPSC lines expressed pluripotency markers, had a normal karyotype and demonstrated the ability to differentiate into derivatives of the three germ layers. Clinical exome sequencing data of the original biosamples of the donors are available in the NCBI SRA database. The generated cell lines are useful as “healthy” control in biomedical studies.

Original languageEnglish
Article number101952
Number of pages4
JournalStem Cell Research
Volume48
Early online date8 Aug 2020
DOIs
Publication statusPublished - 1 Oct 2020

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