Features of solid-phase mechanochemical synthesis of hydroxyapatite doped by copper and zinc ions

Natalia V. Bulina, Olga B. Vinokurova, Natalia V. Eremina, Igor Y. Prosanov, Vyacheslav R. Khusnutdinov, Marina V. Chaikina

Research output: Contribution to journalArticlepeer-review

Abstract

The work shows that single-phase hydroxyapatite doped with zinc or copper ions can be obtained using a solid-phase mechanochemical synthesis after 30 ​min of processing the reaction mixture in a planetary ball mill. To understand the mechanism of incorporating doping elements in the apatite structure, two substitution reactions have been investigated, namely replacement of the calcium and hydroxide ions with copper or zinc ions. The research has shown that, in the synthesized material, the dopant ions mainly take the sites of calcium ions. The degree of substitution can be up to 2 ​mol of substituent per mol of hydroxyapatite. The obtained samples can be used to produce medical bioresorbable items and coatings with antibacterial properties.

Original languageEnglish
Article number121973
JournalJournal of Solid State Chemistry
Volume296
DOIs
Publication statusPublished - Apr 2021

Keywords

  • Copper
  • Doping
  • Hydroxyapatite
  • Mechanochemical synthesis
  • Substitution
  • Zinc

OECD FOS+WOS

  • 1.04.EC CHEMISTRY, INORGANIC & NUCLEAR
  • 1.04.EI CHEMISTRY, PHYSICAL

Fingerprint Dive into the research topics of 'Features of solid-phase mechanochemical synthesis of hydroxyapatite doped by copper and zinc ions'. Together they form a unique fingerprint.

Cite this