Effect of New Antiviral Agent Camphecin on Behavior of Mice

Research output: Contribution to journalArticlepeer-review

Abstract

We studied the effect of camphecin (1,7,7-trimethylbicyclo[2.2.1]heptan-2-ylidene-aminoethanol) on mouse behavior in the open-field test. Camphecin possesses antiviral activity and inhibits viral replication, but its influence on the nervous system is poorly studied. Single camphecin injection produced no significant changes in behavioral patterns. Chronic camphecin administration (5 times over 2 weeks) to mice of different strains had no significant influence on open field behavior (motor, exploratory activity, anxiety, emotional state and vegetative functions). The findings are discussed in the context of neutral influence of camphecin on animal behavior.

Original languageEnglish
Pages (from-to)346-348
Number of pages3
JournalBulletin of Experimental Biology and Medicine
Volume162
Issue number3
DOIs
Publication statusPublished - 1 Jan 2017

Keywords

  • anxiety
  • camphecin
  • locomotor activity

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