Drosophila male-sterile mutation emmenthal specifically affects the mitochondrial morphogenesis

N. V. Dorogova, E. U. Bolobolova, K. A. Akhmetova, S. A. Fedorova

Research output: Contribution to journalArticlepeer-review

3 Citations (Scopus)


Proper mitochondrial morphogenesis is crucial for successful development of motile sperm. It was known that recessive Drosophila melanogaster mutation emm caused anomalies in the formation of a mitochondrial derivative-nebenkern and led to male sterility. Here we identified primary mutation effect and showed that emm is required for the formation and maintenance of inner mitochondrial structure starting from early spermatocytes. Abnormal mitochondria structure affects subsequent cellular processes in spermatogenesis such as meiotic cytokinesis and spermatid elongation.

Original languageEnglish
Pages (from-to)515-520
Number of pages6
Issue number2
Publication statusPublished - 2013
Externally publishedYes


  • Cytokinesis
  • Drosophila melanogaster
  • Emm mutant
  • Meiosis
  • Mitochondria
  • Spermatogenesis


Dive into the research topics of 'Drosophila male-sterile mutation emmenthal specifically affects the mitochondrial morphogenesis'. Together they form a unique fingerprint.

Cite this