Developmental aspects of senescence

E. Yu Brusentsev; M. A. Tikhonova; Yu E. Herbeck; D. S. Ragaeva; I. N. Rozhkova; S. Ya Amstislavsky

doi:10.1134/S1062360417020035

Developmental aspects of senescence

E. Yu Brusentsev, M. A. Tikhonova, Yu E. Herbeck, D. S. Ragaeva, I. N. Rozhkova, S. Ya Amstislavsky

Research output: Contribution to journal › Review article › peer-review

1 Citation (Scopus)

Abstract

Different types of senescence and major theories of aging are reviewed, and mechanisms of this complex biological phenomenon are discussed. Emphasis is placed on changes in the nervous systems of mammals and humans with age. Experimental animal models for studying aging and modern approaches to the correction of age-related deterioration are considered. Chemicals and other factors that may alleviate agerelated disorders and slow down senescence are critically reviewed.

Original language	English
Pages (from-to)	93-105
Number of pages	13
Journal	Russian Journal of Developmental Biology
Volume	48
Issue number	2
DOIs	https://doi.org/10.1134/S1062360417020035
Publication status	Published - 1 Mar 2017

Keywords

aging theories
central nervous system
experimental models of senescence
ontogenesis

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title = "Developmental aspects of senescence",

abstract = "Different types of senescence and major theories of aging are reviewed, and mechanisms of this complex biological phenomenon are discussed. Emphasis is placed on changes in the nervous systems of mammals and humans with age. Experimental animal models for studying aging and modern approaches to the correction of age-related deterioration are considered. Chemicals and other factors that may alleviate agerelated disorders and slow down senescence are critically reviewed.",

keywords = "aging theories, central nervous system, experimental models of senescence, ontogenesis",

author = "Brusentsev, {E. Yu} and Tikhonova, {M. A.} and Herbeck, {Yu E.} and Ragaeva, {D. S.} and Rozhkova, {I. N.} and Amstislavsky, {S. Ya}",

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AU - Tikhonova, M. A.

AU - Herbeck, Yu E.

AU - Ragaeva, D. S.

AU - Rozhkova, I. N.

AU - Amstislavsky, S. Ya

PY - 2017/3/1

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N2 - Different types of senescence and major theories of aging are reviewed, and mechanisms of this complex biological phenomenon are discussed. Emphasis is placed on changes in the nervous systems of mammals and humans with age. Experimental animal models for studying aging and modern approaches to the correction of age-related deterioration are considered. Chemicals and other factors that may alleviate agerelated disorders and slow down senescence are critically reviewed.

AB - Different types of senescence and major theories of aging are reviewed, and mechanisms of this complex biological phenomenon are discussed. Emphasis is placed on changes in the nervous systems of mammals and humans with age. Experimental animal models for studying aging and modern approaches to the correction of age-related deterioration are considered. Chemicals and other factors that may alleviate agerelated disorders and slow down senescence are critically reviewed.

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KW - central nervous system

KW - experimental models of senescence

KW - ontogenesis

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DO - 10.1134/S1062360417020035

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