Developmental aspects of senescence

E. Yu Brusentsev, M. A. Tikhonova, Yu E. Herbeck, D. S. Ragaeva, I. N. Rozhkova, S. Ya Amstislavsky

    Research output: Contribution to journalReview articlepeer-review

    1 Citation (Scopus)


    Different types of senescence and major theories of aging are reviewed, and mechanisms of this complex biological phenomenon are discussed. Emphasis is placed on changes in the nervous systems of mammals and humans with age. Experimental animal models for studying aging and modern approaches to the correction of age-related deterioration are considered. Chemicals and other factors that may alleviate agerelated disorders and slow down senescence are critically reviewed.

    Original languageEnglish
    Pages (from-to)93-105
    Number of pages13
    JournalRussian Journal of Developmental Biology
    Issue number2
    Publication statusPublished - 1 Mar 2017


    • aging theories
    • central nervous system
    • experimental models of senescence
    • ontogenesis

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