Development and Validation of a Method for Determination of a New Effective Inhibitor of Influenza Virus H1N1 in Blood Plasma

Research output: Contribution to journalArticlepeer-review

2 Citations (Scopus)

Abstract

A new GC-MS method for determining an antiviral agent (camphecin) in blood plasma was developed. Sample preparation consisted of precipitating proteins using MeOH. The method was validated for selectivity, calibration curve, accuracy, precision, limit of quantitation, carryover, and stability. The analytical range was 0.1 – 2 μg/mL. The method could be used for pharmacokinetic studies.

Original languageEnglish
Pages (from-to)1102-1105
Number of pages4
JournalPharmaceutical Chemistry Journal
Volume51
Issue number12
DOIs
Publication statusPublished - Mar 2018

Keywords

  • camphecin
  • GC-MS
  • plasma
  • validation
  • A VIRUSES
  • ANTIVIRAL ACTIVITY
  • DERIVATIVES

Fingerprint

Dive into the research topics of 'Development and Validation of a Method for Determination of a New Effective Inhibitor of Influenza Virus H1N1 in Blood Plasma'. Together they form a unique fingerprint.

Cite this