Determination of the Orientation of Phospholipid Molecules in Planar Structures from Raman Spectra

K. A. Okotrub, V. A. Zykova, S. V. Adishchev, N. V. Surovtsev

Research output: Contribution to journalArticlepeer-review

Abstract

A method is proposed for determining the orientation of phospholipid molecules in planar structures from spectra of non-polarized Raman scattering. The method is based on the sensitivity of the intensity of lines of Raman scattering from vibrations of CH2 groups to the orientation of phospholipid molecules. The validity of the method is illustrated on a planar sample of a saturated phospholipid prepared by drying from a solution. The principal component analysis is demonstrated to be a convenient tool for analyzing the spatial distribution of molecule orientations in the sample.

Original languageEnglish
Pages (from-to)495-500
Number of pages6
JournalOptoelectronics, Instrumentation and Data Processing
Volume55
Issue number5
DOIs
Publication statusPublished - 1 Sep 2019

Keywords

  • orientation of molecules
  • phospholipid bilayer
  • planar structure
  • Raman scattering

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