Determination of Citrate Ions in Blood Plasma by Capillary Zone Electrophoresis

Research output: Contribution to journalArticlepeer-review


Abstract: A procedure is developed for the determination of citrate ions in blood plasma by capillary zone electrophoresis at a level of 20‒800 mg/L. The background electrolyte (BGE) was a solution containing 10 mM chromate ions and 40 mM diethanolamine. Sample preparation included protein precipitation with acetonitrile, followed by dilution with a solution containing an internal standard (fluoride ion), and centrifugation. It is shown that the use of the internal standard ensures the account of the change in the migration time of the analyte in the analysis of biological samples. The relative standard deviation of analysis does not exceed 10% for two replicate determinations. The systematic error of the developed procedure was evaluated by the added–found method.

Original languageEnglish
Pages (from-to)906-909
Number of pages4
JournalJournal of Analytical Chemistry
Issue number9
Publication statusPublished - 1 Sep 2018


  • blood plasma
  • capillary electrophoresis
  • citrate ion
  • hemodialysis

Fingerprint Dive into the research topics of 'Determination of Citrate Ions in Blood Plasma by Capillary Zone Electrophoresis'. Together they form a unique fingerprint.

Cite this