Coordination Compounds of Cobalt(II), Nickel(II), and Copper(II) Halides with 2-Methyl-1,2,4-Triazolo[1,5-a]benzimidazole

I. I. Dyukova; T. A. Kuz’menko; V. Yu Komarov; T. S. Sukhikh; E. V. Vorontsova; L. G. Lavrenova

doi:10.1134/S107032841812014X

Coordination Compounds of Cobalt(II), Nickel(II), and Copper(II) Halides with 2-Methyl-1,2,4-Triazolo[1,5-a]benzimidazole

I. I. Dyukova, T. A. Kuz’menko, V. Yu Komarov, T. S. Sukhikh, E. V. Vorontsova, L. G. Lavrenova

Research output: Contribution to journal › Article › peer-review

1 Citation (Scopus)

Abstract

New coordination compounds of Co(II), Ni(II), and Cu(II) halides with 2-methyl-1,2,4-triazolo[1,5-a]benzimidazole (L), [Co(L)₂Cl₂] (Ia), [Ni(L)₂(H₂O)₄]Cl₂ · 4H₂O (II), and [Сu₂(L)₄(µ-Br)₂Br₂] (IIIa), are synthesized. The complexes are studied by X-ray structure analysis (СIF files CCDC nos. 1825006–1825008), electronic (diffuse reflectance) spectroscopy, and IR spectroscopy. In compounds Ia, II, and IIIa, ligand L is coordinated to the metal by the N⁴ atom of the triazole fragment. The study of the cytotoxic effect of the ligand and synthesized complexes on the Hep-2 line (laryngeal cancer cells) shows a considerably higher activity of the copper(II) complex than that of the ligand.

Original language	English
Pages (from-to)	755-764
Number of pages	10
Journal	Russian Journal of Coordination Chemistry/Koordinatsionnaya Khimiya
Volume	44
Issue number	12
DOIs	https://doi.org/10.1134/S107032841812014X
Publication status	Published - 1 Dec 2018

Keywords

2-methyl-1,2,4-triazolo[1,5-a]benzimidazole
3d metals
complexes
cytotoxic activity
electronic spectroscopy
IR spectroscopy
synthesis
X-ray structure analysis
4-triazolo[1
CU(II)
2-methyl-1
COMPLEXES
ANTIBACTERIAL
CO(II)
1,2,4-TRIAZOLE
5-a]benzimidazole
2
PLATINUM(II)
BENZIMIDAZOLE
IMIDAZOLE
ANTIMICROBIAL ACTIVITY
THIABENDAZOLE

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@article{8c844288e0eb4852ae1bec81f6f2e76c,

title = "Coordination Compounds of Cobalt(II), Nickel(II), and Copper(II) Halides with 2-Methyl-1,2,4-Triazolo[1,5-a]benzimidazole",

abstract = "New coordination compounds of Co(II), Ni(II), and Cu(II) halides with 2-methyl-1,2,4-triazolo[1,5-a]benzimidazole (L), [Co(L)2Cl2] (Ia), [Ni(L)2(H2O)4]Cl2 · 4H2O (II), and [Сu2(L)4(µ-Br)2Br2] (IIIa), are synthesized. The complexes are studied by X-ray structure analysis (СIF files CCDC nos. 1825006–1825008), electronic (diffuse reflectance) spectroscopy, and IR spectroscopy. In compounds Ia, II, and IIIa, ligand L is coordinated to the metal by the N4 atom of the triazole fragment. The study of the cytotoxic effect of the ligand and synthesized complexes on the Hep-2 line (laryngeal cancer cells) shows a considerably higher activity of the copper(II) complex than that of the ligand.",

keywords = "2-methyl-1,2,4-triazolo[1,5-a]benzimidazole, 3d metals, complexes, cytotoxic activity, electronic spectroscopy, IR spectroscopy, synthesis, X-ray structure analysis, 4-triazolo[1, CU(II), 2-methyl-1, COMPLEXES, ANTIBACTERIAL, CO(II), 1,2,4-TRIAZOLE, 5-a]benzimidazole, 2, PLATINUM(II), BENZIMIDAZOLE, IMIDAZOLE, ANTIMICROBIAL ACTIVITY, THIABENDAZOLE",

author = "Dyukova, {I. I.} and Kuz{\textquoteright}menko, {T. A.} and Komarov, {V. Yu} and Sukhikh, {T. S.} and Vorontsova, {E. V.} and Lavrenova, {L. G.}",

year = "2018",

month = dec,

day = "1",

doi = "10.1134/S107032841812014X",

language = "English",

volume = "44",

pages = "755--764",

journal = "Russian Journal of Coordination Chemistry/Koordinatsionnaya Khimiya",

issn = "1070-3284",

publisher = "Maik Nauka-Interperiodica Publishing",

number = "12",

}

Coordination Compounds of Cobalt(II), Nickel(II), and Copper(II) Halides with 2-Methyl-1,2,4-Triazolo[1,5-a]benzimidazole. / Dyukova, I. I.; Kuz’menko, T. A.; Komarov, V. Yu; Sukhikh, T. S.; Vorontsova, E. V.; Lavrenova, L. G.

In: Russian Journal of Coordination Chemistry/Koordinatsionnaya Khimiya, Vol. 44, No. 12, 01.12.2018, p. 755-764.

Research output: Contribution to journal › Article › peer-review

TY - JOUR

T1 - Coordination Compounds of Cobalt(II), Nickel(II), and Copper(II) Halides with 2-Methyl-1,2,4-Triazolo[1,5-a]benzimidazole

AU - Dyukova, I. I.

AU - Kuz’menko, T. A.

AU - Komarov, V. Yu

AU - Sukhikh, T. S.

AU - Vorontsova, E. V.

AU - Lavrenova, L. G.

PY - 2018/12/1

Y1 - 2018/12/1

N2 - New coordination compounds of Co(II), Ni(II), and Cu(II) halides with 2-methyl-1,2,4-triazolo[1,5-a]benzimidazole (L), [Co(L)2Cl2] (Ia), [Ni(L)2(H2O)4]Cl2 · 4H2O (II), and [Сu2(L)4(µ-Br)2Br2] (IIIa), are synthesized. The complexes are studied by X-ray structure analysis (СIF files CCDC nos. 1825006–1825008), electronic (diffuse reflectance) spectroscopy, and IR spectroscopy. In compounds Ia, II, and IIIa, ligand L is coordinated to the metal by the N4 atom of the triazole fragment. The study of the cytotoxic effect of the ligand and synthesized complexes on the Hep-2 line (laryngeal cancer cells) shows a considerably higher activity of the copper(II) complex than that of the ligand.

AB - New coordination compounds of Co(II), Ni(II), and Cu(II) halides with 2-methyl-1,2,4-triazolo[1,5-a]benzimidazole (L), [Co(L)2Cl2] (Ia), [Ni(L)2(H2O)4]Cl2 · 4H2O (II), and [Сu2(L)4(µ-Br)2Br2] (IIIa), are synthesized. The complexes are studied by X-ray structure analysis (СIF files CCDC nos. 1825006–1825008), electronic (diffuse reflectance) spectroscopy, and IR spectroscopy. In compounds Ia, II, and IIIa, ligand L is coordinated to the metal by the N4 atom of the triazole fragment. The study of the cytotoxic effect of the ligand and synthesized complexes on the Hep-2 line (laryngeal cancer cells) shows a considerably higher activity of the copper(II) complex than that of the ligand.

KW - 2-methyl-1,2,4-triazolo[1,5-a]benzimidazole

KW - 3d metals

KW - complexes

KW - cytotoxic activity

KW - electronic spectroscopy

KW - IR spectroscopy

KW - synthesis

KW - X-ray structure analysis

KW - 4-triazolo[1

KW - CU(II)

KW - 2-methyl-1

KW - COMPLEXES

KW - ANTIBACTERIAL

KW - CO(II)

KW - 1,2,4-TRIAZOLE

KW - 5-a]benzimidazole

KW - 2

KW - PLATINUM(II)

KW - BENZIMIDAZOLE

KW - IMIDAZOLE

KW - ANTIMICROBIAL ACTIVITY

KW - THIABENDAZOLE

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U2 - 10.1134/S107032841812014X

DO - 10.1134/S107032841812014X

M3 - Article

AN - SCOPUS:85060303094

VL - 44

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EP - 764

JO - Russian Journal of Coordination Chemistry/Koordinatsionnaya Khimiya

JF - Russian Journal of Coordination Chemistry/Koordinatsionnaya Khimiya

SN - 1070-3284

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