Chemical mechanisms of prebiotic chirality amplification

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1 Citation (Scopus)

Abstract

This review article surveys the recent experimental findings that suggest alternative chemical models of directed chirality amplification at the early, prebiotic Earth. It is believed that the chirality amplification step followed the initial emergence of small enantiomeric imbalance and preceded (as a necessary condition) the occurrence of homochiral biopolymers, assembled from enantiomerically pure building blocks. This work focuses on the chemical nature of possible mechanisms of primordial chirality enhancement, without going into detail of the preceding and subsequent phases of origination of biological homochirality and life on Earth. These mechanisms are discussed through the prism of integrity of biological natural selection and chemical kinetic selection.

Original languageEnglish
Article number5689246
Number of pages8
JournalResearch
Volume2020
DOIs
Publication statusPublished - Aug 2020

Keywords

  • ABSOLUTE ASYMMETRIC-SYNTHESIS
  • AUTOAMPLIFICATION
  • AUTOCATALYSIS
  • CONJUNCTION
  • ENANTIOMERIC EXCESSES
  • HOMOCHIRALITY
  • ORIGIN
  • OXIDATIVE KINETIC RESOLUTION
  • PRINCIPLE
  • PYRIMIDYL ALKANOL

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