Application of Natural Polysaccharides in Pharmaceutics

M. V. Khvostov, T. G. Tolstikova, S. A. Borisov, A. V. Dushkin

Research output: Contribution to journalReview articlepeer-review

Abstract

Modern data are presented on the pharmaceutical application of natural polysaccharides, such as pullulan, alginates, hyaluronic acid, dextrans, pectin, chitosan, and arabinogalactan, which are already actively used or can be used in the future for optimizing different drug forms, water solubility and improving bioavailability. The emphasis on natural polysaccharides is made in relation to their good biocompatibility, biodegradation, hydrophilicity, good stability, safety, lack of toxicity, and adhesive properties. The indicated parameters are important and necessary for agents used for drug delivery into the human body.

Original languageEnglish
Pages (from-to)438-450
Number of pages13
JournalRussian Journal of Bioorganic Chemistry
Volume45
Issue number6
DOIs
Publication statusPublished - 1 Nov 2019

Keywords

  • alginates
  • arabinogalactan
  • chitosan
  • dextrans
  • hyaluronic acid
  • increased bioavailability
  • pectin
  • polysaccharides
  • pullulan

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