Abstract

Until recently, DNA repair was almost exclusively considered in the B-DNA context, since non-canonical DNA was not believed t be a significant target for damage in the bulk genome. A paradigm shift that followed the discoveries of functionally important roles of non-canonical DNA and the cases of apparent connection of regulation with DNA damage put DNA repair in non-canonical structures into the focus of active studies. In this work we investigated base excision repair in non-canonical DNA structures involving hairpins, quadruplexes and DNA/RNA heteroduplexes
Original languageEnglish
Pages568
Number of pages1
DOIs
Publication statusPublished - 2020
EventBioinformatics of Genome Regulation and Structure Systems Biology (BGRS/SB-2020): The Twelfth International Multiconference (06-10 July 2020, Novosibirsk, Russia) - ICG SB RAS, Новосибирск, Russian Federation
Duration: 6 Jul 202010 Jul 2020
Conference number: 12
https://bgrssb.icgbio.ru/2020/

Conference

ConferenceBioinformatics of Genome Regulation and Structure Systems Biology (BGRS/SB-2020): The Twelfth International Multiconference (06-10 July 2020, Novosibirsk, Russia)
Abbreviated titleBGRS/SB-2020
CountryRussian Federation
CityНовосибирск
Period06.07.202010.07.2020
Internet address

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