Abstract
The report is about an assessment of a beam at an accelerator neutron source at Budker Institute of Nuclear Physics and its possible application on glioblastoma tumor. An evaluation of the efficacy of boron neutron capture therapy on heterotopic glioblastoma U87 MG in SCID mice using different boron containing drugs was carried out. Accumulation of 10B in tumor and normal tissues was detected using atomic emission spectrometer ICPE-9820 (Shimadzu, Japan). Tumor growth was significantly slower in all irradiated groups from the 7th day after BNCT compared to untreated control group. The differences between experimental groups became significant from the 50th day after BNCT. Liposomal BSH showed better long-term results compared to BPA and non-liposomal BSH.
| Original language | English |
|---|---|
| Title of host publication | 19th International Congress on Neutron Capture Therapy Granada, Spain, September 27th - October 1st, 2021. Book of Abstacts |
| Place of Publication | Вена |
| Publisher | International Atomic Energy Agency |
| Pages | 152 |
| Number of pages | 1 |
| Publication status | Published - 2021 |
| Event | 19th International Congress on Neutron Capture Therapy - Вена, Austria Duration: 27 Sep 2021 → 1 Oct 2021 Conference number: 19 http://www.icnct19.org/ |
Conference
| Conference | 19th International Congress on Neutron Capture Therapy |
|---|---|
| Abbreviated title | ICNCT |
| Country | Austria |
| City | Вена |
| Period | 27.09.2021 → 01.10.2021 |
| Internet address |
OECD FOS+WOS
- 2.02.IQ ENGINEERING, ELECTRICAL & ELECTRONIC
State classification of scientific and technological information
- 47.31 Accelerators of charged particles and plasma