A single-cell view of tissue regeneration in plants

Research output: Contribution to journalReview articlepeer-review

5 Citations (Scopus)


With the development of advanced molecular-genetic and computational technologies it becomes possible to tackle individual cells within a regenerating tissue, to define morphogenetic and cellular changes in space and time by live imaging, to acquire transcriptome status with single-cell RNA sequencing (ScRNA-seq), and to delineate the candidate mechanisms by iterative computational and experimental approaches. Here, we review recent findings and current knowledge on tissue regeneration in plants, focusing on four evolutionarily conserved scenarios that a cell may embark on to facilitate the regeneration of a plant tissue structure lost by injury, namely cell death, division, dedifferentiation, and transdifferentiation. Understanding of these scenarios at single-cell resolution, singularly and in combination, could provide an unprecedented view of tissue regeneration in plants.

Original languageEnglish
Pages (from-to)149-154
Number of pages6
JournalCurrent Opinion in Plant Biology
Early online date22 Oct 2019
Publication statusPublished - Dec 2019


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