Перспективы использования показателей жесткости легочной артерии для оценки прогноза больных с легочной артериальной гипертензией

Translated title of the contribution: Perspectives of using pulmonary arterial stiffness indicators to evaluate the prognosis of patients with pulmonary arterial hypertension

M. A. Simakova, A. Ryzhkov, A. Kyzymly, A. Naimushin, V. L. Lukinov, O. M. Moiseeva

Research output: Contribution to journalArticlepeer-review

1 Citation (Scopus)

Abstract

Objective: the aim of the study was to characterize the mechanical properties of the pulmonary arterial wall (PA) in patients with pulmonary arterial hypertension (PAH) using magnetic resonance imaging (MRI) of the heart, and to determine their diagnostic and prognostic value. Materials and methods: 57 patients with PAH were examined. The diagnosis of PAH was verified according to the recommendations of the ERS/ESC from 2015. All patients underwent a detailed echocardiographic (ECHO) study, MRI of the heart and right heart catheterization (RHC). To calculate the stiffness of the pulmonary artery wall, the MRI and RHC data were used. Results: We identified a correlation between the functional class of PAH and the parameters of hemodynamic, physical performance, ECHO parameters of the right chambers. There were no differences in the stiffness of the pulmonary artery wall, depending on the functional class of PAH. Among the six stiffness indicators, only pulsation index was associated with the structural and functional parameters of the right ventricle and pulmonary vascular resistance. Conclusion: The MRI pulsation index is the simpleststiffness index of the pulmonary artery wall and the most promising one for evaluating the prognosis of patients with PAH
Translated title of the contributionPerspectives of using pulmonary arterial stiffness indicators to evaluate the prognosis of patients with pulmonary arterial hypertension
Original languageRussian
Pages (from-to)86-92
Number of pages7
JournalTerapevticheskii Arkhiv
Volume90
Issue number1
DOIs
Publication statusPublished - 1 Jan 2018
Externally publishedYes

Keywords

  • pulmonary hypertension
  • right ventricular heart failure
  • stiffness of the vessel wall
  • pathophysiology of pulmonary arterial hypertension
  • DISTENSIBILITY
  • Hypertension, Pulmonary/diagnosis
  • Cardiac Catheterization
  • Prognosis
  • Humans
  • Pulmonary Artery
  • Vascular Stiffness
  • Pulmonary hypertension
  • Pathophysiology of pulmonary arterial hypertension
  • Right ventricular heart failure
  • Stiffness of the vessel wall

State classification of scientific and technological information

  • 76 MEDICINE AND HEALTH CARE

Cite this