This review focuses on neural stem cells of Drosophila melanogaster called neuroblasts. Drosophila melanogaster is a well-described and convenient model for studying the fundamental behavior of stem cells and mechanisms underlying cell differentiation. Lots of features demonstrated in the development of the Drosophila's nervous system are also found in humans. Therefore, a detailed study of neuroblasts is an important task for expanding our understanding of the process of cell division and the mechanisms of tumor formation. This review will focus on recent advances of the study of Drosophila neuroblasts including their classification, origin and migration. In addition, we describe in detail the asymmetric division of neuroblasts and its molecular mechanisms.
- Asymmetric division
- Drosophila melanogaster
- 1.06 BIOLOGICAL SCIENCES
State classification of scientific and technological information
- 34 BIOLOGY