A modular visual model of energy metabolism in human skeletal muscle

I. N. Kiselev, I. R. Akberdin, A. Yu Vertyshev, Popov D.V., F. A. Kolpakov

Research output: Contribution to journalArticlepeer-review

4 Citations (Scopus)


The paper presents a modification of a multi-compartmental mathematical model describing the dynamics of intracellular species concentrations and fluxes in human muscle at rest. A modular representation of a complex model is proposed, which provides the possibility of rapid expansion and modification of the model compartments to account for the complex organization of muscle cells and the limitations of the rate of diffusion of metabolites between intracellular compartments. To illustrate the work of the model, intracellular response in human skeletal muscle to acute aerobic two-legged cycle ergometer training was considered.

Translated title of the contributionМодульная графическая модель энергетического метаболизма в клетках скелетной мышцы
Original languageEnglish
Pages (from-to)373-392
Number of pages20
JournalMathematical Biology and Bioinformatics
Issue number2
Publication statusPublished - 1 Jan 2019

State classification of scientific and technological information

  • 34 BIOLOGY


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