Immunohistochemical analysis of active caspase-3 expression in structures of neonatal brain

D. A. Lanshakov; V. V. Bulygina; I. V. Romanova; N. N. Dygalo

doi:10.1007/s10517-009-0563-6

Immunohistochemical analysis of active caspase-3 expression in structures of neonatal brain

D. A. Lanshakov, V. V. Bulygina, I. V. Romanova, N. N. Dygalo

Physiology Section

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6 Citations (Scopus)

Abstract

The hippocampal fields of neonatal rats differ by the level of active caspase-3: dentate gyrus >CA3>CA1>CA2. In the dentate gyrus it was 70% of its maximum value in the cortex, while in CA2 it corresponded to the minimum level in the brain stem. Taking into account the role of caspase-3 in apoptosis, these differences can indicate different intensity of programmed cell death in different fields of the forming hippocampus.

Translated title of the contribution	Иммуногистохимический анализ экспрессии активной каспазы-3 в структурах неонатального головного мозга
Original language	English
Article number	22
Pages (from-to)	635-638
Number of pages	4
Journal	Bulletin of Experimental Biology and Medicine
Volume	147
Issue number	5
DOIs	https://doi.org/10.1007/s10517-009-0563-6
Publication status	Published - 2009

Keywords

Active caspase-3
Brain
Hippocampus
Ontogeny

OECD FOS+WOS

3.01.QA MEDICINE, RESEARCH & EXPERIMENTAL
1.06 BIOLOGICAL SCIENCES

State classification of scientific and technological information

34 BIOLOGY

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title = "Immunohistochemical analysis of active caspase-3 expression in structures of neonatal brain",

abstract = "The hippocampal fields of neonatal rats differ by the level of active caspase-3: dentate gyrus >CA3>CA1>CA2. In the dentate gyrus it was 70% of its maximum value in the cortex, while in CA2 it corresponded to the minimum level in the brain stem. Taking into account the role of caspase-3 in apoptosis, these differences can indicate different intensity of programmed cell death in different fields of the forming hippocampus.",

keywords = "Active caspase-3, Brain, Hippocampus, Ontogeny",

author = "Lanshakov, {D. A.} and Bulygina, {V. V.} and Romanova, {I. V.} and Dygalo, {N. N.}",

note = "Funding Information: The study was supported by the Russian Foundation for Basic Research (grant No. 08-04-00292).",

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AU - Lanshakov, D. A.

AU - Bulygina, V. V.

AU - Romanova, I. V.

AU - Dygalo, N. N.

N1 - Funding Information: The study was supported by the Russian Foundation for Basic Research (grant No. 08-04-00292).

PY - 2009

Y1 - 2009

N2 - The hippocampal fields of neonatal rats differ by the level of active caspase-3: dentate gyrus >CA3>CA1>CA2. In the dentate gyrus it was 70% of its maximum value in the cortex, while in CA2 it corresponded to the minimum level in the brain stem. Taking into account the role of caspase-3 in apoptosis, these differences can indicate different intensity of programmed cell death in different fields of the forming hippocampus.

AB - The hippocampal fields of neonatal rats differ by the level of active caspase-3: dentate gyrus >CA3>CA1>CA2. In the dentate gyrus it was 70% of its maximum value in the cortex, while in CA2 it corresponded to the minimum level in the brain stem. Taking into account the role of caspase-3 in apoptosis, these differences can indicate different intensity of programmed cell death in different fields of the forming hippocampus.

KW - Active caspase-3

KW - Brain

KW - Hippocampus

KW - Ontogeny

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ER -

Immunohistochemical analysis of active caspase-3 expression in structures of neonatal brain

Abstract

Keywords

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