Differentially expressed genes in lower limb varicose vein disease

M. A. Smetanina, F. A. Sipin, E. I. Seliverstov, I. A. Zolotukhin, M. L. Filipenko

Research output: Contribution to journalArticlepeer-review


Lower limb varicose vein disease is the most important type of chronic venous dise ases. At the same time, molecular events associated with pathogenesis of this disease are known extremely fragmentarily and their sequence is not always clear. However, the resear chers are able to decipher possible stages of these processes through investigation of gene expression patterns and their comparison with normal characteristics. This review illustrates the main molecular processes in lower limb varicose vein disease. Moreover, the genes with confirmed differential expression are analyzed.

Translated title of the contributionДифференциально экспрессирующиеся гены при варикозной болезни нижних конечностей
Original languageEnglish
Pages (from-to)122-134
Number of pages13
Issue number2
Publication statusPublished - 1 Jan 2020


  • Gene expression
  • Lower limb varicose vein disease
  • Pathogenesis


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